WHAT IS Lopressor/Metoprolol?

Lopressor/Metoprolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Lopressor/Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.

Lopressor/Metoprolol may also be used for purposes other than those listed in this medication guide.

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT Lopressor/Metoprolol?

Do not stop taking Lopressor/metoprolol without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using Lopressor/metoprolol. Be sure the surgeon knows ahead of time that you are using Lopressor/metoprolol.

Lopressor/Metoprolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Lopressor/metoprolol.

Lopressor/Metoprolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

WHAT SHOULD I DISCUSS WITH MY HEALTHCARE PROVIDER BEFORE TAKING Lopressor/Metoprolol?

Do not use this medication if you are allergic to Lopressor/metoprolol, or if you have:

• a heart problem such as heart block, sick sinus syndrome, or slow heart rate;
• pheochromocytoma; or
• problems with circulation (such as Raynaud's syndrome).

Before taking Lopressor/metoprolol, tell your doctor if you have:

• congestive heart failure;
• myasthenia gravis.
• low blood pressure;
• diabetes;
• liver or kidney disease;
• depression;
• asthma, bronchitis, emphysema;
• a thyroid disorder; or

If you have any of these conditions, you may not be able to use Lopressor/metoprolol, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Lopressor/Metoprolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

WHAT HAPPENS IF I OVERDOSE?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an Lopressor/metoprolol overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).

WHAT HAPPENS IF I MISS A DOSE?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

HOW SHOULD I TAKE Lopressor/Metoprolol?

Take Lopressor/metoprolol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.

Take this medication with a full glass of water.

Take Lopressor/metoprolol at the same time every day.

A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking Lopressor/metoprolol without first talking to your doctor. Stopping suddenly may make your condition worse.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using Lopressor/metoprolol. You may need to briefly stop using Lopressor/metoprolol before having surgery.

Lopressor/Metoprolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Store Lopressor/metoprolol at room temperature away from moisture and heat.

WHAT OTHER DRUGS WILL AFFECT Lopressor/Metoprolol?

Before taking Lopressor/metoprolol, tell your doctor if you are using:

• a diuretic (water pill) such as amiloride (Midamor, Moduretic ), chlorthalidone (Hygroton, Thalitone), Lasix/furosemide ( Lasix ), Oretic/hydrochlorothiazide (HCTZ, HydroDiuril , Hyzaar , Lopressor , Vasoretic, Zestoretic ), Aldactone/spironolactone (Aldactazide, Aldactone ), triamterene (Dyrenium, Maxzide, Dyazide), Demadex/torsemide ( Demadex ), and others; or
• anti-malaria medications such as Aralen/chloroquine ( Aralen ) or hydroxychloroquine (Plaquenil, Quineprox);
• an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or Eldepryl/selegiline ( Eldepryl , Emsam);
• a diabetes medication such as insulin, glyburide (Diabeta, Micronase , Glynase), Glucotrol/glipizide ( Glucotrol ), chlorpropamide (Diabinese), or Glucophage sr/metformin ( Glucophage sr/Glucophage );
• cold medicines, stimulant medicines, or diet pills.
• clonidine (Catapres);
• a heart medication such as Adalat cc er/nifedipine ( Procardia , Adalat cc er/Adalat ), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), Calan sr/verapamil ( Calan sr/Calan , Verelan sr/Verelan , Isoptin sr/Isoptin ), Diltiazem cr/Diltiazem cr/diltiazem ( Cartia , Cardizem cd/Cardizem );
• Lamisil/terbinafine ( Lamisil );
• Digitek/digoxin (digitalis, Lanoxin );
• Norvir/ritonavir ( Norvir );
• medicine for asthma or other breathing disorders, such as Proventil cr/Albuterol cr/albuterol ( Ventolin sulfate/Ventolin , Proventil cr/Proventil ), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), Brethine/terbutaline ( Brethaire , Brethine , Bricanyl), and Uni-dur sr/theophylline (Theo-Dur, Theolair tr/Theolair );
• medicine to treat depression or mental illness, such as Zyban sr/bupropion ( Wellbutrin sr/Wellbutrin , Zyban sr/Zyban ), Rapiflux/fluoxetine ( Prozac , Sarafem ), Paxil/paroxetine ( Paxil ), Mellaril/thioridazine ( Mellaril ), and others;

If you are using any of these drugs, you may not be able to take Lopressor/metoprolol, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect Lopressor/metoprolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Lopressor/Metoprolol SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• feeling short of breath, even with mild exertion;
• slow or uneven heartbeats;
• swelling of your ankles or feet;
• depression; or
• feeling light-headed, fainting;
• cold feeling in your hands and feet.
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

Other less serious side effects are more likely to occur, such as:

• anxiety, nervousness.
• decreased sex drive, impotence, or difficulty having an orgasm;
• vomiting;
• tired feeling; or
• sleep problems (insomnia);

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

WHAT SHOULD I AVOID WHILE TAKING Lopressor/Metoprolol?

Lopressor/Metoprolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Lopressor/metoprolol.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.