WHAT IS Moduretic/Amiloride-hydrochlorothiazide?

AMILORIDE ; Esidrix/HYDROCHLOROTHIAZIDE is a combination of two types of diuretics. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure and heart failure. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

WHAT SIDE EFFECTS MAY I NOTICE FROM Moduretic/Amiloride-hydrochlorothiazide?

Side effects that you should report to your doctor or health care professional as soon as possible:

• fast, irregular heartbeat
• yellowing of the eyes or skin
• feeling faint or lightheaded, falls
• muscle pain, cramps
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• unusual bleeding
• unusually weak or tired
• worsened gout pain
• fever
• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• trouble passing urine or change in the amount of urine
• black or tarry stools
• numbness, tingling in hands or feet
• breathing problems

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• irregular menstrual periods
• blurred vision
• stomach pain
• enlarged, tender breasts
• headache
• dry mouth, increased thirst
• change in sex drive or performance
• constipation

This list may not describe all possible side effects.

WHAT IF I MISS A DOSE?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

WHAT SHOULD I TELL MY HEALTH CARE PROVIDERS BEFORE I TAKE Moduretic/Amiloride-hydrochlorothiazide?

They need to know if you have any of these conditions:

• small amount of urine
• pregnant or trying to get pregnant
• kidney disease
• unusual or allergic reaction to amiloride , Esidrix/hydrochlorothiazide, other diuretics, sulfa drugs, other medicines, foods, dyes, or preservatives
• breast-feeding
• immune system problems, like lupus
• diabetes

WHAT SHOULD I WATCH FOR WHILE USING Moduretic/Amiloride-hydrochlorothiazide?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor what your blood pressure should be, and when you should contact them. If you are diabetic, check your blood sugar as directed.

You may need to be on a special diet while taking this medicine. Ask your doctor. You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

WHERE SHOULD I KEEP Moduretic/Amiloride-hydrochlorothiazide?

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

Keep out of the reach of children.

WHAT MAY INTERACT WITH Moduretic/Amiloride-hydrochlorothiazide?

Do not take this medicine with any of the following:

• potassium sparing diuretics
• quinidine
• eplerenone

This medicine may also interact with the following:

• Prograf/tacrolimus
• potassium supplements
• steroid hormones like cortisone, hydrocortisone, Deltasone/prednisone
• neuromuscular blockers used during surgery
• antiinflammatory drugs, NSAIDs like Motrin/ibuprofen
• barbiturate medicines for sleep or seizure control
• muscle relaxers
• Gengraf/cyclosporine
• Lithobid/lithium
• medicines for diabetes
• some medicines for pain like codeine
• ACE inhibitors for heart or kidney disease like Capoten/captopril, lisinopril
• cholestyramine, colestipol
• alcohol
• medicines for high blood pressure or heart failure
• other diuretics

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

HOW SHOULD I USE Moduretic/Amiloride-hydrochlorothiazide?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take it at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not take at bedtime. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.